Tacrolimus/Protopic for mild to moderate psoriasis
A new study has found tacrolimus cream (brand name Protopic) effective for mild to moderate psoriasis. Both 0.1% and 0.5% formulations beat the placebo by more than 20% in this 10 week trial. (Interestingly, the 0.1% strength did as well as the 0.5% in this study.)
Tacrolimus appeared safe in the study, although the study was 10 weeks, not the 10 or more years that many psoriasis patients might need a treatment.
Tacrolimus (Protopic) cream, marketed by Astellas Pharma, is currently FDA-approved for the treatment of moderate to severe atopic dermatitis (eczema), but is already used by some dermatologists off-label to treat psoriasis. It is a non-steroid alternative.
In 2005, the FDA pushed for a new warning for tacrolimus concerning "a possible risk of cancer." The American Academy of Dermatology strongly disagreed with the FDA's facts and conclusions.
When Psoriasis Cure Now spoke before an FDA Advisory Committee Hearing in 2005 in support of moving some prescription steroids to over-the-counter use, we touched briefly on this tacrolimus controversy.
Tacrolimus appeared safe in the study, although the study was 10 weeks, not the 10 or more years that many psoriasis patients might need a treatment.
Tacrolimus (Protopic) cream, marketed by Astellas Pharma, is currently FDA-approved for the treatment of moderate to severe atopic dermatitis (eczema), but is already used by some dermatologists off-label to treat psoriasis. It is a non-steroid alternative.
In 2005, the FDA pushed for a new warning for tacrolimus concerning "a possible risk of cancer." The American Academy of Dermatology strongly disagreed with the FDA's facts and conclusions.
When Psoriasis Cure Now spoke before an FDA Advisory Committee Hearing in 2005 in support of moving some prescription steroids to over-the-counter use, we touched briefly on this tacrolimus controversy.
posted by Psoriasis Cure Now at 9:40 PM
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