Targretin (Bexarotene)
BRAND NAME: Targretin
GENERIC NAME: Bexarotene
EXPERIMENTAL/INTERNAL COMPANY NAME: LG 1069 |
|
| DRUG USE (P OR PsA) | METHOD OF DELIVERY | DEVELOPING COMPANY/COMPANIES |
| Plaque psoriasis | Topical gel/used with UVB phototherapy | Ligand Pharmaceuticals, University of Medicine and Dentistry New Jersey |
Description and Comments
Targretin (Bexarotene) is a special type of retinoid called a rexinoid and is a close relative of the other retinoids
used to treat psoriasis: Tazorac (tazarotene) and Soriatane (acitretin). All three drugs are derivatives of Vitamin A. Targretin differs from the others in that it binds to a different protein inside cells. In a Phase II clinical trial, targretin combined with UVB therapy achieved better results than UVB therapy alone. Targretin has even helped some patients who used other retinoids without success.
Other News and Links
T-Cell Activation Key to Targretin Gel Efficacy (2006)
